Testosterone-Science
for health and longevity
ANDROMAN
Last Updated
2025-09-26 14:18:01
A person doing a TRT self-injection.
TRT is often administered via self-injection, offering convenience and stable hormone levels.

What is TRT?

TRT microdosing means giving small, frequent testosterone injections (for example, every 2–5 days) to keep blood levels steady when the body’s natural hormone “thermostat” (the HPG axis) isn’t producing enough testosterone. There are many ways of doing TRT but injections provide more consistent, better dosable absorption than gels, patches or pills, and are much cheaper. TRT restores both virility and vitality in men with low testosterone. With the right dose it does not only relieves symptoms but can also bring a renewed sense of well-being. Studies link higher testosterone levels also to lower mortality risk and fewer chronic diseases. TRT is easy to do, affordable and generally safe. TRT includes doing regular blood work and health evaluation. Guidance of a specialist is prefered. TRT is not needed for men with enough natural testosterone.

Testosterone Replacement Therapy (TRT) Infographic
This infographic summarizes the key benefits of Testosterone Replacement Therapy. Click to enlarge.

TRT for Andropause

Men going through andropause—a drop in testosterone as they age—deal with more than just regular getting older. They often face ongoing tiredness, low sex drive, trouble with erections, losing muscle, mood changes, and fuzzy thinking. Over time, low testosterone also raises heart disease risk, weakens bones, messes up how the body handles energy, and cuts down on healthy years of life.

Even though it affects millions of men, andropause is still something people avoid talking about. Many suffer quietly because of society's negative views on men showing weakness and the wrong idea that these changes can't be helped. This drop in male hormones is often not spotted, but it's a condition that deeply affects men's lives. TRT helps by fixing the hormone shortage to bring back energy, sexual function, muscle power, and clear thinking. TRT brings back energy for life—letting men regain their physical strength, steady emotions, and excitement for living, while possibly adding more healthy years and longer life.

TRT for T2D/Obesity

Testosterone therapy can give real help to middle-aged men caught in the loop of type 2 diabetes and extra weight. Too much body fat turns testosterone into estrogen faster, which drops testosterone levels too low. Lower testosterone then makes it tougher to manage blood sugar and easier to pack on more fat—making the problems that lowered testosterone even worse to start with. This hormone drop often appears as constant tiredness, low drive, mood changes, and weak muscles—turning healthy eating and regular workouts into tough challenges.

By getting testosterone back to normal levels, TRT helps break this loop. Men usually feel more energy, better moods, and stronger muscles, which makes it much easier to keep up with diet and exercise changes. At the same time, testosterone boosts how the body handles insulin, aids in losing fat, and helps keep lean muscle. In this way, TRT doesn't just fix low testosterone—it teams up with lifestyle changes to better control blood sugar and improve body shape.

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TRT for Longevity

TRT is a solid way to manage risks for middle-aged men with low testosterone who don't hit the medical cutoff for hypogonadism. The goal is to bring levels back to normal to cut down on aging-related health risks—improving body shape, how the body uses insulin, fat levels in blood, blood pressure, swelling, and blood vessel health—helping lead to less overall heart and metabolic problems over time and lower risk of death from any cause. Testosterone levels below 16 nmol/L (460 ng/dL) already increase metabolic risks.

TRT boosts both energy and manhood in older men. It improves sex drive and function, steadies mood and drive, increases energy, keeps muscle mass and strength, and protects bone strength and overall body ability. With regular blood checks and watching for side effects, TRT is seen as safe. In the end, it means balancing the upsides of longer life and daily energy against possible downsides like lower fertility and the challenge of quitting treatment later on (which might not be possible).

Consequences, Risks, Side Effects

TRT is often for life, your balls shrink and there can be side-effects. Weighing the pros and cons is a personal decision.

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Safety

Based on the extensive clinical evidence from multiple high-quality studies, TRT demonstrates an overall favorable safety profile.

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Protocol and Home Kit

Learn how to set up and follow a proper TRT protocol at home—from injection supplies and dosing schedule to monitoring and Biometrics.

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